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David L Hughes Selected Research

Dolichol Monophosphate Mannose

3/2009First small molecular inhibitors of T. brucei dolicholphosphate mannose synthase (DPMS), a validated drug target in African sleeping sickness.

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David L Hughes Research Topics

Disease

1COVID-19
12/2020
1Giardiasis
10/2018
1Breast Neoplasms (Breast Cancer)
10/2017
1Adenoma (Adenomas)
10/2017
1Lung Neoplasms (Lung Cancer)
10/2017
1Edema (Dropsy)
01/2017
1Hyperalgesia
01/2017
1African Trypanosomiasis (Nagana)
03/2009
1Acquired Immunodeficiency Syndrome (AIDS)
08/2006

Drug/Important Bio-Agent (IBA)

2Pharmaceutical PreparationsIBA
10/2018 - 03/2009
1Chalcone (Benzalacetophenone)IBA
12/2020
1SARS-CoV-2 3C-like proteinaseIBA
12/2020
1Proteins (Proteins, Gene)FDA Link
12/2020
1LigandsIBA
12/2020
1Albendazole (Albenza)FDA Link
10/2018
1Cisplatin (Platino)FDA LinkGeneric
10/2017
1EstersIBA
10/2017
1carbeneIBA
10/2017
1Dopamine (Intropin)FDA LinkGeneric
01/2017
1Dinoprostone (PGE2)FDA Link
01/2017
1CarrageenanIBA
01/2017
1BucladesineIBA
01/2017
1Dipyrone (Metamizole)IBA
01/2017
1Dolichol Monophosphate MannoseIBA
03/2009
13- (3,5- dichlorophenyl)- 1- methyl- 2,5- pyrrolidinedione (DPMS)IBA
03/2009
1BoratesIBA
08/2006
1SaltsIBA
08/2006

Therapy/Procedure

1Therapeutics
03/2009